RRM1 monoclonal antibody (M04), clone 1D6
产品名称: RRM1 monoclonal antibody (M04), clone 1D6
英文名称: RRM1 monoclonal antibody (M04), clone 1D6
产品编号: H00006240-M04
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant RRM1.
- Immunogen:
- RRM1 (NP_001024.1, 593 a.a. ~ 792 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- IRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKLTSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEEKERNTAAMVCSLENRDECLMCGS
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (47.41 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- RRM1 monoclonal antibody (M04), clone 1D6. Western Blot analysis of RRM1 expression in Raw 264.7.
- Protocol Download
- Western Blot (Cell lysate)
- RRM1 monoclonal antibody (M04), clone 1D6. Western Blot analysis of RRM1 expression in K-562.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of RRM1 expression in transfected 293T cell line by RRM1 monoclonal antibody (M04), clone 1D6.
Lane 1: RRM1 transfected lysate (Predicted MW: 90.1 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Entrez GeneID:
- 6240
- GeneBank Accession#:
- NM_001033.2
- Protein Accession#:
- NP_001024.1
- Gene Name:
- RRM1
- Gene Alias:
- R1,RIR1,RR1
- Gene Description:
- ribonucleotide reductase M1
- Omim ID:
- 180410
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq
- Other Designations:
- ribonucleoside-diphosphate reductase M1 chain,ribonucleotide reductase M1 polypeptide,ribonucleotide reductase, R1 subunit,ribonucleotide reductase, large subunit
- Related Disease
- Abortion, Spontaneous
- Adenocarcinoma
- Breast cancer
- Breast Neoplasms
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Pancreatic Ductal
- Carcinoma, Squamous Cell
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Lung Neoplasms
- Neoplasm Recurrence, Local
- Neoplasms, Second Primary
- Neutropenia
- Pancreatic Neoplasms